Portsmouth must create a bigger gap between themselves and the teams near the bottom, and they have a chance to do so when they host struggling Blackburn.
Blackburn, led by new head coach Valerien Ismael, have not won in their last four matches, losing three in a row and sliding out of the playoff positions.
Team news
Portsmouth are dealing with several injuries, including their top scorer Callum Lang who is one of six players ruled out for the remainder of the season.
It is unlikely that centre-backs Conor Shaughnessy and Rob Atkinson will be fit for this game.
Left-back Harry Pickering is set to make his first appearance for Blackburn in three months. However, Blackburn will be missing several key players like Scott Wharton, Andreas Weimann, and Augustus Kargbo.
The stats
Portsmouth have earned 32 of their 42 points (76%) at Fratton Park.
In their last 13 home league matches, Portsmouth have won nine and lost only two, defeating teams like Coventry and Leeds.
They have conceded 61 goals, with only Cardiff and Plymouth allowing more goals this season.
After a five-game winless streak, Blackburn have dropped to ninth place. Under Ismael, they have only picked up one point from the last 12 available and suffered three consecutive defeats.
Blackburn have lost six of their previous seven away games.
Prediction
Both teams are struggling with injuries and this match at Fratton Park is crucial for their respective seasons.
Portsmouth had moved clear of the relegation zone but suffered two unlucky 2-1 defeats before the break, leaving them just four points above the drop zone.
Meanwhile, Blackburn are without a win in a month and need a turnaround in their form to secure a playoff spot.
Ismael will be hoping that the two-week break has allowed his team to adjust to his tactics following Eustace's departure to Derby.
Blackburn can expect a tough test at Fratton Park, where Portsmouth have been strong. This presents a good opportunity for Portsmouth to secure their 10th win in 14 home games and move closer to safety.