Arsenal faced another setback as they suffered a 1-0 loss to Inter Milan at the San Siro.
Despite dominating parts of the game, Mikel Arteta's team was left disappointed after a contentious penalty decision in the first half, where Mikel Merino was penalized for a handball.
Hakan Calhanoglu converted the penalty kick, and despite their efforts to find the equalizer, Arsenal succumbed to their second consecutive defeat in four days, their first loss in the Champions League this season.
Ahead of the match in Milan, Arsenal's preparations were overshadowed by the surprising resignation of sporting director Edu.
Edu, who had been credited for the team's recent successes, scored in a memorable 5-1 victory for Arsene Wenger's team 21 years ago at the same venue. However, history did not repeat itself on this occasion.
Arsenal's Premier League aspirations took a hit, especially without the presence of the injured Declan Rice, who narrowly escaped falling behind early in the game.
After weathering some early pressure, Arsenal managed to regain their composure. They had their moments, with Bukayo Saka and Gabriel Martinelli threatening the Inter defense.
Despite showing promise from set-pieces, Arsenal found themselves trailing at halftime due to a controversial penalty decision against Merino.
In the second half, Arsenal continued to push for an equalizer, coming close on several occasions but failing to find the back of the net against a resilient Inter side.
Arteta's frustration grew as the game progressed, culminating in a bizarre moment where he handled the ball during play, earning himself a caution from the referee.
Despite late efforts and the introduction of Martin Odegaard, Arsenal could not salvage a point from the match, ultimately falling to Inter Milan.